Tokyo, Oct. 16 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059416) titled 'A prospective cohort study on predictors of renal function decline in a population at risk for the onset and progression of chronic kidney disease' on Oct. 15.

Study Type: Observational

Primary Sponsor: Institute - Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

Condition: Condition - chronic kidney disease Classification by malignancy - Others Genomic information - YES

Objective: Narrative objectives1 - The objective of this study is to identify predictors associated with renal function decline in patients with chronic kidney disease (CKD) or those at risk of developing CKD, such as individuals with diabetes, hypertension, or obesity. We will utilize clinical information obtained in routine medical practice, along with regularly collected blood and urine test data and stored blood samples. Through this approach, we aim to explore useful indicators for the early prediction of CKD progression risk and to generate foundational data for the future implementation of personalized medicine and interventional studies aimed at slowing disease progression. Basic objectives2 - Others

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - 1. Patients visiting the Department of Nephrology, Hypertension, and Endocrinology at Nihon University Itabashi Hospital who are diagnosed with chronic kidney disease, or those with diabetes, hypertension, or obesity who are considered to be at high risk of developing chronic kidney disease in the future (from September 2025 to May 2030). 2. healthy individuals who underwent medical checkups at Hatogaya Hospital Key exclusion criteria - 1. Persons who express their unwillingness to participate in this study. 2. Persons deemed by the principal investigator to be unsuitable for inclusion in this study for any reason. Target Size - 1600

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2025 Year 09 Month 26 Day Date of IRB - 2025 Year 09 Month 18 Day Anticipated trial start date - 2025 Year 09 Month 26 Day Last follow-up date - 2030 Year 09 Month 01 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067941

Disclaimer: Curated by HT Syndication.