Tokyo, Aug. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062416) titled 'Prospective observational study of ultrasound-guided adductor canal block combined with popliteal plexus block for postoperative analgesia after tibial plateau fracture surgery' on July 31.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Uncontrolled

Primary Sponsor: Institute - Iwate Prefectural Ofunato Hospital

Condition: Condition - tibial plateau fracture Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To prospectively evaluate the proportion of patients requiring rescue analgesia (NSAID administration or initiation of intravenous patient-controlled analgesia [IVPCA]) within 24 hours after surgery, as well as perioperative outcomes, in patients undergoing tibial plateau fracture surgery who receive ultrasound-guided adductor canal block (ACB) combined with popliteal plexus block (PPB). Basic objectives2 - Safety,Efficacy

Intervention: Interventions/Control_1 - After induction of general anesthesia, ultrasound-guided adductor canal block (ACB) and popliteal plexus block (PPB) will be performed using 10 mL of 0.25% levobupivacaine for each block (total 20 mL, 50 mg) without adjuvants. Acetaminophen will be administered every 6 hours postoperatively. Rescue analgesia will consist of NSAID administration, followed by intravenous patient-controlled analgesia (IVPCA) if required.

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - 1.Age 18 years or older. 2.Patients undergoing open reduction and internal fixation for tibial plateau fracture under general anesthesia at Iwate Prefectural Ofunato Hospital. 3.Able to understand the Numeric Rating Scale (NRS). 4.Written informed consent obtained from the patient. Key exclusion criteria - 1.Refusal to participate. 2.Allergy to local anesthetics. 3.Infection at the injection site. 4.Coagulopathy or antithrombotic therapy contraindicating peripheral nerve block. 5.Severe pre-existing neurological deficits. 6.Suspected or confirmed acute compartment syndrome or planned fasciotomy. 7.Inability to provide written informed consent. 8.Pregnancy. 9.Patients considered unsuitable by the attending physician. Target Size - 10

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 07 Month 15 Day Date of IRB - 2026 Year 07 Month 21 Day Anticipated trial start date - 2026 Year 07 Month 31 Day Last follow-up date - 2031 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071428

Disclaimer: Curated by HT Syndication.