Clinical Trial: A retrospective and prospective observational study of patients with severe heart failure or shock admitted to the intensive care unit (Japan)

Tokyo, May 17 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061600) titled 'A retrospective and prospective observational study of patients with severe heart failure or shock admitted to the intensive care unit' on May 17.

Study Type: Observational

Primary Sponsor: Institute - Kokura memoria hospital

Condition: Condition - acute heart failure, cardiogenic shock, sepsis, acute myocardial infarction, fulminant myocarditis, pulmonary embolism, ventricular arrhythmias, cardiac arrest, PCCS and post-cardiac arrest syndrome Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Despite advances in contemporary cardiovascular intensive care, mortality among patients who develop cardiogenic shock due to acute myocardial infarction remains high, with approximately half of affected patients dying. Recently, the use of the Impella mechanical circulatory support device was shown to reduce mortality in patients with cardiogenic shock. In addition, transition from an open ICU model to a semi-closed ICU model has also been associated with improved survival. In parallel, there has been growing interest in optimizing hemodynamic management strategies for critically ill patients with cardiovascular disease and shock. Against this background, we established the present database to support future improvements in the management and outcomes of patients with severe cardiovascular disease and shock. Basic objectives2 - Safety,Efficacy

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - Eligible patients were those admitted to the intensive care unit with severe heart failure, cardiogenic shock, sepsis, or those who received mechanical circulatory support, and who met the following inclusion and exclusion criteria. Key exclusion criteria - Age of 100 years or older Refusal to participate in the study Target Size - 1500

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2010 Year 03 Month 31 Day Date of IRB - 2025 Year 12 Month 05 Day Anticipated trial start date - 2010 Year 04 Month 01 Day Last follow-up date - 2029 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070474

Disclaimer: Curated by HT Syndication.