Tokyo, Sept. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058170) titled 'A study on quantitative assessment of hemostatic function in patients with thrombocytopenia due to liver cirrhosis' on Sept. 1.

Study Type: Observational

Primary Sponsor: Institute - Nagoya University

Condition: Condition - liver cirrhosis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The study aimed to examine the correlation coefficient between bleeding time and hemostatic capacity measured by the HD assay in cirrhotic patients with platelet counts below 90,000/microL, as well as to investigate the correlation between hemostatic capacity obtained from the HD assay and various parameters such as blood coagulation factors, and to assess bleeding risk and bleeding complications following invasive procedures Basic objectives2 - Efficacy

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Clinically diagnosed with liver cirrhosis Has a platelet count of either 20,000-90,000/microL or 90,000-150,000/microL 18 years of age or older Key exclusion criteria - Patients requested to be excluded from the main study Patients with congenital platelet function disorders such as Glanzmann's thrombasthenia or Bernard-Soulier syndrome or von Willebrand disease Patients currently taking antiplatelet or anticoagulant medications Patients with severe anemia or hypoalbuminemia Patients with embolic diseases such as myocardial infarction, cerebral infarction, or pulmonary embolism Patients presenting with DIC due to severe infections, active bleeding, cancer, hematologic malignancies, or poor general condition Any other patients deemed unsuitable for safe participation in this study by the attending physician Target Size - 70

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 06 Month 13 Day Anticipated trial start date - 2025 Year 09 Month 01 Day Last follow-up date - 2027 Year 09 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000066491

Disclaimer: Curated by HT Syndication.