Clinical Trial: A study on the 5-year positivity rate of cardiac amyloidosis in patients with amyloid deposition detected during surgery for carpal tunnel syndrome or trigger finger who were negative for cardiac amyloidosis at the time of surgery (Japan)

Tokyo, April 22 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061345) titled 'A study of cardiac amyloidosis 5 years after surgery in patients with amyloid deposition detected during carpal tunnel syndrome or trigger finger surgery' on April 21.

Study Type: Observational

Primary Sponsor: Institute - Saiseikai Yamaguchi General Hospital

Condition: Condition - carpal tunnel syndrome, trigger finger, amyloid deposition, cardiac amyloidosis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This study aims to determine the proportion of patients who test positive for cardiac amyloidosis at the five-year follow-up assessment, focusing on cases in which histological amyloid deposits were identified during surgery for carpal tunnel syndrome or trigger finger, yet who tested negative for cardiac amyloidosis at the time of surgery. Basic objectives2 - Others

Eligibility: Age-lower limit - Not applicable Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients who underwent surgery for carpal tunnel syndrome or trigger finger at Saiseikai Yamaguchi General Hospital from February 2020 onward. Patients with amyloid deposition confirmed by pathological examination of tissue collected during surgery. Patients judged to be negative for cardiac amyloidosis at the time of surgery based on cardiovascular evaluation. Patients who can be contacted at the time of the 5-year follow-up evaluation. Patients from whom informed consent for participation in this study can be obtained Key exclusion criteria - Patients who do not give their consent to participate in the study Patients for whom it is difficult to obtain the information required for the 5-year follow-up or to carry out the necessary tests Patients deemed unsuitable by the principal investigator Target Size - 250

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 03 Month 31 Day Anticipated trial start date - 2026 Year 04 Month 01 Day Last follow-up date - 2031 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070191

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