Tokyo, Oct. 18 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059448) titled 'A Study on the Stress-Relieving Effects of Green VR Environments: A Volunteer Study' on Oct. 18.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Self control

Primary Sponsor: Institute - KANAGAWA DENTAL UNIVERSITY

Condition: Condition - Dental Anesthesiology Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - Previously, VR incorporating green hues has demonstrated the potential to suppress the hypothalamic-pituitary-adrenal (HPA) axis and reduce stress. Activation of the HPA axis leads to cortisol secretion. Cortisol increases sensitivity to vasoconstrictors (such as noradrenaline and angiotensin II) and elevates peripheral vascular resistance by suppressing the production of vasodilators like nitric oxide (NO). Therefore, this study hypothesises that VR incorporating green may suppress cortisol production and thereby inhibit peripheral vascular resistance, leading to the implementation of the research described below. Basic objectives2 - Others

Intervention: Interventions/Control_1 - This study is a cohort study involving stress loading on the same subjects, with measurements of each parameter taken before and after exposure to a green VR environment.

Eligibility: Age-lower limit - 20 years-old

Gender - Male and Female Key inclusion criteria - Healthy adults (American Society of Anesthesiologists physical status classification (ASA-PS classification of 1 or 2)) Key exclusion criteria - None Target Size - 20

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 06 Month 24 Day Date of IRB - 2025 Year 06 Month 24 Day Anticipated trial start date - 2025 Year 10 Month 18 Day Last follow-up date - 2026 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067936

Disclaimer: Curated by HT Syndication.