Tokyo, Aug. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058670) titled 'A systematic review of the functionality of "Lutein and zeaxanthin" for improving sight function in healthy adults (updated version from 2023)' on Aug. 1.

Study Type: Others,meta-analysis etc

Primary Sponsor: Institute - Oryza Oil and Fat Chemical Co., Ltd.

Condition: Condition - The subjects were healthy adults (excluding those under 18 years old, pregnant women, and lactating women) Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The objective of this study is to investigate whether the intake of lutein and zeaxanthin effect sight function in healthy adults, including the latest RCTs. Basic objectives2 - Efficacy

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - P-Participant: Participant The subjects were healthy adults (excluding those under 18 years old, pregnant women, and lactating women)

I-intervention: Intervention (food) characteristics Continuous intake of lutein and zeaxanthin, Unlimited dosage forms, period and follow-up period. Studies involving interventions with a 5:1 ratio of "lutein, zeaxanthin" will be included to ensure equivalence with our lutein and zeaxanthin containing raw materials.

C-Comparison: Comparison Placebo (The placebo's formulation is not specified)

O-Outcome: Outcome The primary outcome: MPOD (Macular Pigment Optical Density) The secondary outcome: Photostress recovery, Glare sensitivity, Chromatic contrast sensitivity

S-Study design: Study design Randomized parallel group controlled trials or randomized crossover trials Key exclusion criteria - The literature which does not meet PICOS, such as conference abstracts (conference proceedings) that are not original articles will be excluded.

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 07 Month 31 Day Anticipated trial start date - 2025 Year 08 Month 01 Day Last follow-up date - 2025 Year 08 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067090

Disclaimer: Curated by HT Syndication.