Tokyo, Sept. 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062924) titled 'A study on pre-treatment assessment and treatment outcomes in older patients with diffuse large B-cell lymphoma' on Sept. 14.
Study Type:
Observational
Primary Sponsor:
Institute - Asahikawa Red Cross Hospital
Condition:
Condition - Diffuse large B-cell lymphoma
Classification by malignancy - Malignancy
Genomic information - NO
Objective:
Narrative objectives1 - To evaluate the predictive performance of existing geriatric assessment and prognostic indices for treatment completion in older patients (75 years or older) with DLBCL receiving curative-intent first-line therapy, and to explore whether social determinants of health (availability of social support, transportation access, nutritional status, medication management, and disease-related functional decline) provide additional predictive value beyond existing indices.
Basic objectives2 - Others
Eligibility:
Age-lower limit - 75
years-old
=
Gender - Male and Female
Key inclusion criteria - - Histologically confirmed DLBCL aged 75 years or older (main analysis) or 65-74 years with pre-treatment geriatric assessment (exploratory)
- Pre-treatment geriatric assessment completed before curative-intent first-line therapy
- Written informed consent obtained
Key exclusion criteria - - Primary CNS lymphoma
- High-grade B-cell lymphoma (MYC/BCL2 rearrangement)
- Insufficient pre-treatment information
- Patient refusal
Target Size - 150
Recruitment Status:
Recruitment status - Enrolling by invitation
Date of protocol fixation - 2026 Year 08 Month 25 Day
Date of IRB - 2026 Year 08 Month 25 Day
Anticipated trial start date - 2026 Year 09 Month 14 Day
Last follow-up date - 2035 Year 12 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072012
Disclaimer: Curated by HT Syndication.
