Tokyo, Oct. 20 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063342) titled 'Effects of Chocolate Odour on Appetite and Resistance Exercise Performance in Healthy Men' on Oct. 19.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Randomized Blinding - Double blind -all involved are blinded Control - Placebo

Primary Sponsor: Institute - Universiti Malaya

Condition: Condition - Appetite regulation and resistance exercise performance under overnight-fasted conditions in healthy resistance-trained adults. Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To investigate the acute effects of chocolate odour exposure on subjective appetite and resistance exercise performance in healthy resistance-trained men under overnight-fasted conditions, and to determine whether changes in appetite perception are accompanied by corresponding changes in circulating ghrelin and glucagon-like peptide-1 (GLP-1). Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - 90DC (90% dark-chocolate odour): Participants were exposed to a dark-chocolate olfactory stimulus prepared using 36 g of 100% cocoa dark chocolate, 3.8 mL of distilled water, and 2.0 mL of propylene glycol (approximately 40 mL final volume). Odour exposure lasted 30 s at 0, 1, 8, and 15 min during the pre-exercise assessment period and was repeated for 30 s immediately before each of four back-squat sets and four bench-press sets. Each participant completed one trial under this condition. Interventions/Control_2 - 60MC (60% milk-chocolate odour): Participants were exposed to a milk-chocolate olfactory stimulus prepared using 12 g of 100% cocoa dark chocolate, 22.8 mL of whole milk, 3.8 mL of distilled water, and 2.0 mL of propylene glycol (approximately 40 mL final volume). The exposure schedule was identical to that of 90DC, consisting of 30-s exposures at 0, 1, 8, and 15 min before exercise and immediately before each of four back-squat and four bench-press sets. Each participant completed one trial under this condition.

Eligibility: Age-lower limit - 18 years-old = Gender - Male Key inclusion criteria - 1. Healthy adult men. 2. Engaged in resistance training at least twice per week for a minimum of one year. 3. Non-smokers. 4. Habitual breakfast consumers. 5. No aversion to cocoa-related or sweet food odours. 6. Willing and able to provide written informed consent and comply with the experimental procedures. Key exclusion criteria - 1. Self-reported olfactory dysfunction. 2. Metabolic or cardiovascular disease. 3. History of substance abuse. 4. Musculoskeletal injury that could impair resistance exercise performance. Target Size - 14

Recruitment Status: Recruitment status - Completed Date of protocol fixation - 2024 Year 02 Month 01 Day Date of IRB - 2024 Year 07 Month 12 Day Anticipated trial start date - 2024 Year 03 Month 01 Day Last follow-up date - 2025 Year 09 Month 10 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072500

Disclaimer: Curated by HT Syndication.