Tokyo, Sept. 3 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062787) titled 'Effects of Multi-Load Resistance Training on Muscle and Physical Function in Middle-Aged and Older Adults' on Sept. 2.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -no one is blinded Control - Active

Primary Sponsor: Institute - Nippon Sport Science University

Condition: Condition - Age-related decline in muscle mass, muscle strength, and physical function Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To compare the effects of multiple-load within-set resistance training with low-load resistance training on muscle hypertrophy, muscle strength, power, physical function, vascular function, and cognitive function in middle-aged and older adults. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - MLT group: Participants perform supervised resistance training twice per week for 6 weeks, for a total of 12 sessions. For the parallel squat, each set consists of 2 repetitions at 85 percent of 1RM, followed by 3 repetitions at 70 percent of 1RM and 6 repetitions at 55 percent of 1RM. Two sets are performed. All concentric actions are performed with maximal effort. Participants also perform the bench press, lat pulldown, Romanian deadlift, back lunge, and kettlebell swing. Interventions/Control_2 - LL group: Participants perform supervised resistance training twice per week for 6 weeks, for a total of 12 sessions. For the parallel squat, participants perform 4 sets of 6 repetitions at 55 percent of 1RM. All concentric actions are performed with maximal effort. Participants also perform the bench press, lat pulldown, Romanian deadlift, back lunge, and kettlebell swing.

Eligibility: Age-lower limit - 40 years-old

Gender - Male and Female Key inclusion criteria - 1. Healthy middle-aged or older adults. 2. Individuals who are able to independently perform a parallel squat. 3. Individuals who are able to participate in supervised training twice per week for 6 weeks, for a total of 12 sessions. 4. Individuals who provide written informed consent after receiving an explanation of the study procedures. Key exclusion criteria - 1. Individuals with pain or musculoskeletal injuries that may interfere with the safe performance of resistance training. 2. Individuals who are unable to perform a parallel squat. 3. Individuals who are unable to participate in supervised training twice per week for 6 weeks, for a total of 12 sessions. 4. Individuals considered unsuitable for participation by the principal investigator for safety or study-related reasons. Target Size - 60

Recruitment Status: Recruitment status - Completed Date of protocol fixation - 2024 Year 04 Month 16 Day Date of IRB - 2022 Year 12 Month 19 Day Anticipated trial start date - 2024 Year 06 Month 17 Day Last follow-up date - 2024 Year 08 Month 04 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071880

Disclaimer: Curated by HT Syndication.