Tokyo, Oct. 25 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063385) titled 'Effects of Toe Strength Training on Foot Muscle Size and Activity' on Oct. 23.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Open -no one is blinded Control - No treatment

Primary Sponsor: Institute - Ritsumeikan University

Condition: Condition - Healthy young adults Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The purpose of this study is to investigate the effects of toe flexor strength training on the morphology and activity of individual plantar intrinsic foot muscles. In addition, this study aims to examine whether the activity of the plantar intrinsic foot muscles differs according to the positions of the interphalangeal and metatarsophalangeal joints during toe flexion force production, and whether training-induced changes in foot muscle morphology, toe flexor strength, foot structure, and balance performance differ according to the toe movement used during training. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Participants perform toe flexor strength training using a toe gripping action twice weekly for 12 weeks. Each training session consists of five sets of 10 repetitions of 5-s toe flexion contractions followed by 5-s rest periods. Training intensity is prescribed relative to maximal toe flexor strength and progressively increased throughout the intervention period. Interventions/Control_2 - Participants perform toe flexor strength training using a toe pushing action twice weekly for 12 weeks. Each training session consists of five sets of 10 repetitions of 5-s toe flexion contractions followed by 5-s rest periods. Training intensity is prescribed relative to maximal toe flexor strength and progressively increased throughout the intervention period.

Eligibility: Age-lower limit - 18 years-old

Gender - Male and Female Key inclusion criteria - 1. Healthy young adult men and women aged 18 years or older and younger than 39 years. 2. Individuals who receive an explanation of the study and provide informed consent to participate. Key exclusion criteria - Individuals meeting any of the following criteria will be excluded:

1. Individuals with symptoms suggestive of a serious physical or mental disorder or injury at the time of enrollment. 2. Individuals who are unable to walk independently. 3. Individuals who are or may be pregnant. 4. Individuals who, after receiving an explanation of the study, are unable to provide consent to participate. 5. Individuals with cardiac or cardiovascular disease, implanted ferromagnetic materials, or claustrophobia that may increase the risk associated with magnetic resonance imaging. 6. Individuals who habitually perform training targeting the foot or lower-leg muscles. 7. Individuals with orthopedic disorders of the foot or ankle. Target Size - 60

Recruitment Status: Recruitment status - Enrolling by invitation Date of protocol fixation - 2023 Year 12 Month 01 Day Date of IRB - 2024 Year 03 Month 28 Day Anticipated trial start date - 2024 Year 05 Month 01 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072553

Disclaimer: Curated by HT Syndication.