Tokyo, Sept. 18 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062950) titled 'Effects of 15-minute water walking in a hydrogen pool on blood flow' on Sept. 18.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Non-randomized Blinding - Open -no one is blinded Control - No treatment

Primary Sponsor: Institute - Muse Dermatology and Pain Clinic

Condition: Condition - Healthy Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To investigate the acute effect of 15-minute water walking in a hydrogen-enriched water pool on peripheral blood flow by comparing it with water walking in a pool without hydrogen bubbling in the same participants. The study also exploratively evaluates the effects on physiological outcomes, including blood lactate concentration, urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), peripheral oxygen saturation (SpO2), heart rate, perfusion index (PI), Subjective Well Being Inventory (SUBI) questionnaire. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Hydrogen condition: Participants performed 15 minutes of water walking in a 32 degrees C experimental pool. Molecular hydrogen gas generated by the HX1600 inhalation system (Helix Japan Co., Ltd.) was continuously bubbled into the pool water during the intervention. Before the start of walking, the dissolved hydrogen concentration was measured near the water surface at the center of the pool using a hydrogen concentration meter (Field New Co., Ltd.) and confirmed to be approximately 1.0 ppm. Hydrogen bubbling was continued throughout the 15-minute walking intervention. Subjects walked back and forth in a 1.5 m x 3.0 m pool at a constant pace of 5 cycles per minute (approximately 25 m/min). Interventions/Control_2 - Control condition: Participants performed 15 minutes of water walking in a 32 degrees C experimental pool without bubbling molecular hydrogen gas. The dissolved hydrogen concentration of the pool water was measured using the same hydrogen concentration meter and confirmed to be 0 ppm. Subjects walked back and forth in a 1.5 m x 3.0 m pool at a constant pace of 5 cycles per minute (approximately 25 m/min).

Eligibility: Age-lower limit - 35 years-old = Gender - Male and Female Key inclusion criteria - Inclusion criteria were: (1) age between 55 and 80 years; (2) ability to perform light aquatic exercise safely; (3) absence of chronic medication use affecting circulation or metabolism; and (4) provision of written informed consent. Key exclusion criteria - Exclusion criteria included: (1) history of cardiovascular, pulmonary, or metabolic disease; (2) active dermatologic conditions that could interfere with water immersion; (3) psychiatric disorders or cognitive impairment; and (4) inability to complete both experimental sessions. Target Size - 11

Recruitment Status: Recruitment status - Completed Date of protocol fixation - 2026 Year 04 Month 01 Day Date of IRB - 2026 Year 03 Month 01 Day Anticipated trial start date - 2026 Year 04 Month 01 Day Last follow-up date - 2026 Year 07 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072043

Disclaimer: Curated by HT Syndication.