Tokyo, Feb. 4 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000060354) titled 'Efficacy of Tapering Programmed Intermittent Bolus in Quadratus Lumborum Block - Double-Blind Randomized Trial -' on Feb. 4.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Randomized Blinding - Double blind -all involved are blinded Control - Active

Primary Sponsor: Institute - Hiroshima University

Condition: Condition - Hip Osteoarthritis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This study compares the efficacy of tapering programmed intermittent bolus (tPIB) versus continuous infusion (CI) in patients undergoing total hip arthroplasty (THA) under general anesthesia with quadratus lumborum block (QLB) for osteoarthritis of the hip. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Tapering Programmed Intermittent Bolus Interventions/Control_2 - Continuous infusion

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients aged 20 years or older at the time of consent acquisition, patients scheduled for elective total hip arthroplasty (THA) under general anesthesia with spinal anesthesia for osteoarthritis of the hip, patients with an ASA-PS classification of Class I to III, and patients for whom written informed consent for participation in this study can be obtained. Key exclusion criteria - Patients unable to report VAS scores, patients whose QLB was discontinued mid-procedure, patients with inadequate conduction anesthesia effect at the end of anesthesia, patients undergoing bilateral simultaneous surgery or reoperation, and patients deemed unsuitable by the principal investigator or co-investigator. Target Size - 44

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 02 Month 04 Day Anticipated trial start date - 2026 Year 02 Month 20 Day Last follow-up date - 2028 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000069048

Disclaimer: Curated by HT Syndication.