Tokyo, July 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062196) titled 'Examination of the cleaning effect of continuous toothpaste use' on July 15.

Study Type: Interventional

Study Design: Basic Design - Cross-over Randomization - Randomized Blinding - Double blind -all involved are blinded Control - Active

Primary Sponsor: Institute - Kao Corporation

Condition: Condition - Not applicable Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To Evaluate the Cleaning effect of toothpaste NP214 Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Use toothpaste NP214 over 2 times a day for 2 weeks Interventions/Control_2 - Use placebo toothpaste over 2 times a day for 2 weeks

Eligibility: Age-lower limit - 20 years-old = Gender - Male and Female Key inclusion criteria - 1. Human aged 20-59 Key exclusion criteria - 1. Individuals with severe allergies or other drug hypersensitivities 2. Individuals with one of the five major diseases (cancer, stroke, acute myocardial infarction, diabetes, or mental illness) who are currently undergoing treatment at a medical facility or are scheduled for surgery or other procedures 3. Pregnant women, women who may be pregnant, or women who are breastfeeding 4. Individuals who have taken antibiotics within the past 3 months 5. Individuals currently participating in other human trials related to oral care or food intake trials 6. Individuals who have had a tooth extracted or undergone dental surgery within the past 3 months 7. Individuals currently receiving oral treatment at a dental clinic 8. Individuals with five or more missing teeth at the time of enrollment (excluding wisdom tooth extractions and extractions due to orthodontic treatment) 9. Individuals with visible oral trauma at the time of enrollment 10. Individuals with severe gingivitis at the time of recruitment 11. Individuals who smoke one or more cigarettes per day at the time of recruitment 12. Individuals who clean their tongue at least once a month at the time of recruitment 13. Individuals deemed unsuitable as study participants by the principal investigator due to violations of compliance obligations or other reasons" Target Size - 20

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 07 Month 06 Day Date of IRB - 2026 Year 07 Month 06 Day Anticipated trial start date - 2026 Year 07 Month 15 Day Last follow-up date - 2027 Year 06 Month 30 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071175

Disclaimer: Curated by HT Syndication.