Tokyo, Aug. 1 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061826) titled 'Elucidating the Neurophysiological Mechanisms Underlying Early Motor Learning Following Transcranial Direct Current Stimulation Over the Dorsolateral Prefrontal Cortex: A Magnetic Resonance Spectroscopy Study' on July 31.
Study Type:
Interventional
Study Design:
Basic Design - Parallel
Randomization - Randomized
Blinding - Double blind -all involved are blinded
Control - Placebo
Primary Sponsor:
Institute - Hokkaido University
Condition:
Condition - healthy adults
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - This study aims to elucidate the neurophysiological effects of tDCS applied over the left DLPFC on early motor learning using MRS.
Basic objectives2 - Efficacy
Intervention:
Interventions/Control_1 - 1) Online tDCS group
2 mA for 20 minutes
Interventions/Control_2 - 2) Offline tDCS group
2 mA for 20 minutes
Eligibility:
Age-lower limit - 18
years-old
Gender - Male and Female
Key inclusion criteria - 1. No history of psychiatric or neurological disorders
2. A person who signed a written informed consent
3. Over 70 points on the Edinburgh Handedness Questionnaire Inventory (Oldfield, 1971)
Key exclusion criteria - 1. History of developmental disabilities or psychiatric disorders
2. MRI examinations are contraindicated for individuals with magnetic materials or implanted medical devices in their bodies, as well as those with claustrophobia.
3. Individuals with evident neurological deficits attributable to stroke
4. Individuals with an increased risk of bleeding, a history of serious adverse events during blood sampling, skin infection or lesions at the venipuncture site, severe fear of blood sampling that precludes safe collection, or who are pregnant or may be pregnant
Target Size - 78
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 07 Month 31 Day
Anticipated trial start date - 2026 Year 08 Month 01 Day
Last follow-up date - 2028 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070727
Disclaimer: Curated by HT Syndication.