Tokyo, Sept. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062759) titled 'A study of changes in gait before and after treatment and factors associated with gait in patients with joint, spinal, and neurological disorders' on Sept. 1.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Self control

Primary Sponsor: Institute - Ehime University

Condition: Condition - Osteoarthritis, osteonecrosis of the femoral head, chronic spinal disorders, Parkinson's disease, and parkinsonian syndromes Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The objective of this study is to quantitatively evaluate gait before and after treatment in patients with joint, spinal, and neurological disorders using biomechanical analysis and to identify factors associated with gait and changes in gait after treatment by examining their relationships with patient characteristics, physical findings, imaging findings, and patient-reported outcomes. Basic objectives2 - Others

Intervention: Interventions/Control_1 - Surgical treatment for joint and spinal disorders and pharmacological treatment for Parkinson's disease and parkinsonian syndromes are provided as part of routine clinical care. Treatment is determined by the attending physician according to each patient's clinical condition, and no treatment is assigned by the study protocol. Gait, physical findings, imaging findings, and patient-reported outcomes are assessed before treatment and within one year after treatment.

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - 1. Patients undergoing surgical treatment for osteoarthritis, osteonecrosis of the femur, or chronic spinal disorders at our institution, or patients receiving treatment for Parkinson's disease or parkinsonian syndromes at our institution 2. Patients who can walk on level ground without assistance at the time of study enrollment 3. Patients who are able to answer questions regarding their subjective symptoms 4. Patients who are able to understand and respond to instructions and questions related to the study procedures Key exclusion criteria - 1. Patients who are unable to complete patient-reported outcome assessments because of dementia or other conditions 2. Patients considered by the investigators to be unable to participate in or complete follow-up because of their health status 3. Patients considered by the investigators to have severe psychosocial disorders that could substantially affect study participation or study outcomes 4. Patients scheduled to participate in another clinical trial or clinical study within 30 days 5. Patients in a protected status, including those who are unable to provide valid consent because of impaired decision-making capacity Target Size - 300

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2026 Year 08 Month 24 Day Date of IRB - 2026 Year 08 Month 24 Day Anticipated trial start date - 2026 Year 08 Month 24 Day Last follow-up date - 2030 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000071853

Disclaimer: Curated by HT Syndication.