Tokyo, Nov. 15 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063632) titled 'Changes in Joint Gap Before and After Medial Meniscus Resection During Total Knee Arthroplasty' on Nov. 15.

Study Type: Observational

Primary Sponsor: Institute - Minamikawa Orthopaedic Hospital

Condition: Condition - Knee osteoarthritis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The primary objective of this study is to quantify changes in the medial joint gap at 0 degrees es of extension and 90 degrees of flexion before and after resection of the residual medial meniscus during total knee arthroplasty. Secondary objectives are to evaluate changes in the lateral joint gap, center gap, and tilt, and to explore associations between residual medial meniscal height and width and changes in the joint gap. Basic objectives2 - Others

Eligibility: Age-lower limit - 18 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - 1. Patients scheduled to undergo primary total knee arthroplasty (TKA) for knee osteoarthritis. 2. Patients aged 18 years or older. 3. Patients scheduled to undergo resection of the anterior cruciate ligament, posterior cruciate ligament, lateral meniscus, and medial meniscus as part of routine surgery. 4. Patients in whom intraoperative joint gap measurements can be performed according to the study protocol. 5. Patients who provide written informed consent after receiving an explanation of the study. Key exclusion criteria - 1. Patients undergoing revision total knee arthroplasty. 2. Patients without evaluable residual medial meniscal tissue due to previous total meniscectomy or other causes. 3. Patients with infectious joint disease. 4. Patients with severe ligament insufficiency or bone defects that prevent safe intraoperative gap measurements. 5. Patients requiring medial meniscus resection for clinical reasons before the study measurements. 6. Patients considered unsuitable for the study by the principal investigator for safety reasons. Target Size - 60

Recruitment Status: Recruitment status - Enrolling by invitation Date of protocol fixation - 2026 Year 10 Month 22 Day Date of IRB - 2026 Year 10 Month 28 Day Anticipated trial start date - 2026 Year 11 Month 04 Day Last follow-up date - 2028 Year 10 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072825

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