Tokyo, Oct. 16 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063135) titled 'Online Experiment on the Coping Effects of Non-Alcoholic Beer' on Oct. 16.

Study Type: Interventional

Study Design: Basic Design - Parallel Randomization - Non-randomized Blinding - Single blind -participants are blinded Control - No treatment

Primary Sponsor: Institute - NTT DATA INSTITUTE OF MANAGEMENT CONSULTING,Inc.

Condition: Condition - Healthy males Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - This study is expected to elucidate the psychological mechanisms underlying the consumption of non-alcoholic beer and mood-regulating behaviors under stressful conditions, thereby providing fundamental knowledge that may contribute to the development of novel beverages and the proposal of drinking behaviors that support the maintenance of psychological and physical well-being even under stressful circumstances.In addition, as a secondary objective, this study will explore how the selection of emotion regulation strategies changes in response to changes in stress levels. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Non-alcoholic beer group: Participants will consume one bottle of non-alcoholic beer every 15 minutes, for a total of two bottles over a 30-minute period. Every 15 minutes, participants will be instructed to press the reaction button on Zoom to confirm that they have not left the screen. Interventions/Control_2 - Control Group: Participants will remain seated at rest for 30 minutes. To ensure that they remain present and in front of the screen, they will be instructed to click a Zoom reaction button every 10 minutes.

Eligibility: Age-lower limit - 20 years-old

Gender - Male Key inclusion criteria - Participants who indicate their willingness to participate and provide informed consent after understanding the study explanation will be included in the research. In this study, participants will be recruited from the NTT Com Research Monitor, a panel managed by NTT Com Online Marketing Solutions. The NTT Com Research Monitor consists ofapproximately 8 million registered individuals ranging in age from their teens to their seventies. This service regularly conducts web-based surveys and interviews to collect opinionson systems, policies, and other topics. All registered members have agreed to the terms and conditions regarding information provision, including the handling of personal data,through NTT Com Research. Participants must meet all of the following criteria:

1)Individuals who understand the contents of this study and provide consent to participate. 2)Healthy men aged 20 to 59 years. 3)Individuals who do not smoke. 4)Able to comfortably consume two 350-mL cans of non-alcoholic beer over approximately 30 minutes, at a rate of approximately one can every 15 minutes. 5)Able to store the study beverages in a refrigerator from the time of receipt until the day of the study. The study beverages consist of two 350-mL cans of Asahi ZERO non-alcoholic beer (alcohol content: 0.00%; amount of pure alcohol: 0 g). 6)Individuals who can participate in the study alone from their home via Zoom on the study day. 7)Individuals who have a stable internet connection and are able to use Zoom. Key exclusion criteria - Individuals who meet any of the following criteria will be excluded:

1. Individuals whose alcohol consumption habits, assessed using the screening questionnaire, exceed the predefined threshold, specifically the AUDIT score of 8 or higher. 2. Individuals for whom alcohol consumption may cause adverse health effects. 3. Individuals who have been advised by a physician to restrict or avoid alcohol consumption, or who need to avoid alcohol consumption due to an underlying medical condition or medication use. 4. Individuals who currently smoke. 5. Individuals who may have difficulty meeting the study environment or study conditions, such as an unstable internet connection, excessive background noise, difficulty remainingseated for an extended period, or difficulty following study instructions. 6. Individuals who have previously participated in an online study on psychological tasks in interpersonal situations conducted by the research team, including the beer study conducted in December 2025 (UMIN Trial ID: UMIN000059814) and the music study conducted from June to July 2026 (UMIN Trial ID: UMIN000062040). Target Size - 90

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 09 Month 28 Day Date of IRB - 2026 Year 09 Month 10 Day Anticipated trial start date - 2026 Year 10 Month 16 Day Last follow-up date - 2027 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072214

Disclaimer: Curated by HT Syndication.