Tokyo, Aug. 30 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058934) titled 'Prognostic impact of MES 1 inflammatory extent on remission maintenance in ulcerative colitis' on Aug. 29.

Study Type: Observational

Primary Sponsor: Institute - Dokkyo Medical University School of Medicine

Condition: Condition - Ulcerative colitis Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - The aim of this study was to retrospectively analyze the impact of the extent of inflammation distribution on the remission maintenance rate in patients with UC evaluated as MES 1 and to reevaluate whether all MES 1 inflammation should be treated equally or not. Basic objectives2 - Others

Eligibility: Age-lower limit - 15 years-old = Gender - Male and Female Key inclusion criteria - Patients with UC who were treated at the Department of Gastroenterology, Dokkyo Medical University Hospital between January 1, 2008, and December 31, 2023, had an MES of 0 or 1 at the initial endoscopic assessment after remission induction therapy without any change in remission maintenance therapy, and had available follow-up data for two years after the endoscopy were enrolled. Key exclusion criteria - The following cases were excluded from the study: cases with left-sided colitis or proctitis; cases in which no endoscopic examination was performed after remission induction; cases in which total colonoscopy was not performed; cases that had an MES of 2 or 3 at the initial endoscopic assessment after remission induction therapy; cases in which the clinical course could not be followed for two years after endoscopy; cases with a history of colonic surgery; cases receiving immunosuppressive therapy for other diseases; cases in which the patient refused to participate in the study; and cases deemed inappropriate for inclusion in this study by the investigators. Target Size - 300

Recruitment Status: Recruitment status - No longer recruiting Date of protocol fixation - 2025 Year 08 Month 29 Day Date of IRB - 2024 Year 12 Month 04 Day Anticipated trial start date - 2025 Year 08 Month 29 Day Last follow-up date - 2025 Year 12 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067400

Disclaimer: Curated by HT Syndication.