Tokyo, June 4 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061774) titled 'The Effects of Local Anesthetics on the Proliferation and Multipotency of Synovial Stem Cells' on June 2.
Study Type:
Interventional
Study Design:
Basic Design - Single arm
Randomization - Non-randomized
Blinding - Open -no one is blinded
Control - Self control
Primary Sponsor:
Institute - Institute of Science Tokyo
Condition:
Condition - Knee Osteoarthritis
Classification by malignancy - Others
Genomic information - NO
Objective:
Narrative objectives1 - We will investigate the effects of local anesthetics on the proliferation and differentiation of synovial-derived stem cells isolated and cultured from synovial tissue obtained from the knee, which is scheduled for surgical resection.
Basic objectives2 - Others
Intervention:
Interventions/Control_1 - Administer a local anesthetic to the site prior to synovial fluid aspiration
Eligibility:
Age-lower limit - 18
years-old
<=
Age-upper limit - Not applicable
Gender - Male and Female
Key inclusion criteria - Patients scheduled to undergo total knee replacement surgery at the Department of Orthopedics, Institute of Science Tokyo Hospital due to osteoarthritis of the knee, starting from the date the research was approved
Key exclusion criteria - Individuals suspected of having an infection.
Individuals deemed medically unsuitable for other reasons.
Target Size - 50
Recruitment Status:
Recruitment status - Preinitiation
Date of protocol fixation - 2026 Year 06 Month 02 Day
Anticipated trial start date - 2026 Year 07 Month 01 Day
Last follow-up date - 2028 Year 03 Month 31 Day
To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000070681
Disclaimer: Curated by HT Syndication.
