Tokyo, Nov. 17 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000059714) titled 'The importance of microvascular dysfunction in patients with chronic thromboembolic pulmonary hypertension' on Nov. 17.

Study Type: Observational

Primary Sponsor: Institute - Osaka Metropolitan University

Condition: Condition - Chronic thromboembolic pulmonary hypertension Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - In this study, we will observe the degree of pulmonary microvascular dysfunction in CTEPH patients undergoing BPA treatment using a pressure wire and the CoroFlow Cardiovascular System. Since the effectiveness of BPA treatment strategies using this system has been reported in previous studies, the aim of this study is to deepen the understanding of the pathophysiology of pulmonary microvascular dysfunction from the data obtained during BPA treatment using this system. As mentioned above, there is currently no established index for quantifying the degree of pulmonary microcirculation. Using microcirculation indices obtained with a pressure wire and the CoroFlow Cardiovascular System, we aim to establish indicators that contribute to predicting post-BPA exercise tolerance and optimizing the distribution of pulmonary blood flow. Basic objectives2 - Others

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - 1. Patients diagnosed with CTEPH 2. Patients judged eligible for BPA treatment 3. Patients aged 20 years or older at the time of obtaining consent Key exclusion criteria - None Target Size - 50

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2025 Year 10 Month 27 Day Date of IRB - 2025 Year 10 Month 27 Day Anticipated trial start date - 2025 Year 11 Month 17 Day Last follow-up date - 2030 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000068297

Disclaimer: Curated by HT Syndication.