Tokyo, Oct. 20 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063341) titled 'The Relationship Between the Neurophysiological Characteristics of the Posterior Parietal Cortex and Upper Limb Motor Function' on Oct. 19.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Self control

Primary Sponsor: Institute - Niigata University of Health and Welfare

Condition: Condition - healthy adults Classification by malignancy - Others Genomic information - NO

Objective: Narrative objectives1 - To clarify the relationship between the neurophysiological characteristics of the occipito-parietal cortex and upper limb motor function Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - During voluntary movement, a single transcranial magnetic stimulation (TMS) pulse is delivered to the posterior parietal cortex (PPC). During stimulation, the subject moves the index finger of the right hand with a constant force, and muscle activity in the right hand is recorded using electromyography (EMG). The effects of PPC stimulation during movement on muscle activity are evaluated based on the resulting changes in muscle activity. At rest, we apply a double-pulse transcranial magnetic stimulation (TMS) to the posterior parietal cortex (PPC) and the primary motor cortex (M1). We record the electromyographic (EMG) responses elicited by stimulation of M1 and evaluate the neurophysiological interaction between the PPC and M1 by comparing the condition in which M1 is stimulated alone with the condition in which M1 is stimulated following PPC stimulation. We will conduct a visual tracking task in which participants move the index finger of their right hand in sync with a target waveform displayed on a monitor. We will calculate the error between the target waveform and the actual finger movement to evaluate finger motor function.

Eligibility: Age-lower limit - 18 years-old = Gender - Male and Female Key inclusion criteria - We will use the university's internal email system to notify undergraduate and graduate students of the call for research participants. We will accept as research participants only those students who express an interest in this study and have fully understood its content, and who voluntarily agree to participate in the experiment of their own free will. The eligibility criteria require participants to be between 18 and 27 years of age. Key exclusion criteria - Participants with implanted metal devices (such as pacemakers), those with claustrophobia, and those with a history of seizures will be excluded from the study. Target Size - 20

Recruitment Status: Recruitment status - Preinitiation Date of protocol fixation - 2026 Year 10 Month 19 Day Anticipated trial start date - 2026 Year 10 Month 26 Day Last follow-up date - 2028 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000072502

Disclaimer: Curated by HT Syndication.