Tokyo, Aug. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058671) titled 'whole brain radiotherapy for metastatic brain tumors, scalp sparing radiotherapy using IMRT: multi-insitutional study' on Aug. 1.

Study Type: Interventional

Study Design: Basic Design - Single arm Randomization - Non-randomized Blinding - Open -no one is blinded Control - Uncontrolled

Primary Sponsor: Institute - Juntendo University

Condition: Condition - metastatic brain tumor Classification by malignancy - Malignancy Genomic information - NO

Objective: Narrative objectives1 - CT data showed that Scalp Sparing IMRT(SS-IMRT) can deliver the required brain dose while sparing scalp hair. However, it is necessary to demonstrate that this is possible in clinical practice and that scalp hair can be preserved as calculated on the treatment planning machine. Follow-up after SS-IMRT will be similar to that in our previous prospective observational study, and the purpose of this study is to compare the results with the baseline data to demonstrate that SS-IMRT can achieve initial hair preservation while maintaining the required brain dose. Basic objectives2 - Efficacy

Intervention: Interventions/Control_1 - Employing IMRT, reduce the dose to the scalp during whole brain radiotherapy

Eligibility: Age-lower limit - 20 years-old <= Age-upper limit - Not applicable Gender - Male and Female Key inclusion criteria - Patients with metastatic brain tumors who will undergo whole-brain radiotherapy using 3D treatment planning system at participating institutions Patients who have provided written consent to participate in the study Patients who are expected to survive for at least one month Key exclusion criteria - Patients who have previously received radiation therapy to the head Target Size - 40

Recruitment Status: Recruitment status - Open public recruiting Date of protocol fixation - 2023 Year 03 Month 24 Day Date of IRB - 2023 Year 03 Month 24 Day Anticipated trial start date - 2023 Year 03 Month 24 Day Last follow-up date - 2027 Year 03 Month 31 Day

To know more, visit https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000067091

Disclaimer: Curated by HT Syndication.