Japan, March 5 -- CELLTRION INC has got intellectual property rights for 'EPITOPE OF HEPATITIS B VIRUS SURFACE ANTIGEN AND BINDING MOLECULE SPECIFICALLY BINDING TO SAME FOR NEUTRALIZING HEPATITIS B VIRUS.' Other related details are as follows:
Application Number: JP,2021-169772
Category (FI): C07K16/08,G01N33/50@Z,G01N33/15@Z,C12Q1/02,C07K14/02,C07K16/082,C12N1/21,C12N15/36,C12P21/08,A61K39/395@D,A61K39/395@S,A61P1/16,A61P31/20
Stage: PROBLEM TO BE SOLVED: To provide an epitope of hepatitis B virus surface antigen and a binding molecule specifically binding to the same for neutralizing hepatitis B virus.SOLUTION: The present invention relates to an epitope specific to hepatitis B virus surface antigen and a binding molecule binding to the same for neutralizing hepatitis B virus. Since the epitope provided by the present invention is produced by forming a three-dimensional structure and does not comprise an a-determinant, by which escape mutation is induced against an administration of existing vaccines or HBIg, a composition comprising an antibody biding to the epitope or a vaccine composition comprising the epitope has a very low possibility of causing a decrease in efficacy due to escape mutation. Therefore, such an antibody or vaccine composition can be very effectively used in prevention and/or treatment of HBV.SELECTED DRAWING: None (Grant)
Filing Date: Oct. 15, 2021
Publication Date: Feb. 22, 2022
The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100
Disclaimer: Curated by HT Syndication.
