Japan Intellectual Property Rights: LENTIVIRAL PACKAGING SYSTEM, LENTIVIRUS PRODUCED THEREBY, AND CELL TRANSDUCED WITH LENTIVIRUS AS WELL AS METHOD PROVIDED FOR USING IT TO IMPROVE YIELD OF LENTIVIRUS IN HOST CELLS

Japan, July 14 -- PELL BIO MED TECHNOLOGY CO LTD has got intellectual property rights for 'LENTIVIRAL PACKAGING SYSTEM, LENTIVIRUS PRODUCED THEREBY, AND CELL TRANSDUCED WITH LENTIVIRUS AS WELL AS METHOD PROVIDED FOR USING IT TO IMPROVE YIELD OF LENTIVIRUS IN HOST CELLS.' Other related details are as follows:

Application Number: JP,2021-142315

Category (FI): C12N15/47,C12N15/49,A61K35/28,A61K35/17@Z,A61P35/00,C12N7/01,C12N5/0775,C12N5/0783,C12N15/867@Z,C12N5/10,A61K35/17

Stage: PROBLEM TO BE SOLVED: To provide a lentivirus packaging system capable of improving virus production efficiency without compromising safety.SOLUTION: Provided is a lentiviral packaging system. The system comprises: a transfer plasmid containing the nucleotide sequence of the TAR chimeric 5'LTR (trans-activation response element-reserved chimeric 5'long terminal repeat); at least one packaging plasmid comprising the nucleotide sequence of a gene encoding a TAR RNA binding protein, the nucleotide sequence of the rev gene, the nucleotide sequence of the gag gene, and the nucleotide sequence of the pol gene; and an envelope plasmid.SELECTED DRAWING: Figure 3 (Grant)

Filing Date: Sept. 1, 2021

Publication Date: Nov. 10, 2022

The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100

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