Japan, Feb. 24 -- SHINO-TEST CORP has got intellectual property rights for 'MEASURING METHOD OF HMGB1 IN SPECIMEN AND MEASUREMENT REAGENT AND METHOD FOR SUPPRESSING NON-SPECIFIC AGGREGATION OF ANTI-HMGB1 ANTIBODY IMMOBILIZED CARRIER, AND METHOD FOR SUPPRESSING RISE OF REAGENT BLANK WHEN MEASURING HMGB1 IN SPECIMEN.' Other related details are as follows:
Application Number: JP,2021-213989
Category (FI): C07K16/18,G01N33/53@D,G01N33/543,581@D,G01N33/543,581@A
Stage: PROBLEM TO BE SOLVED: To provide a measuring method of HMGB1 in a specimen suppressing non-specific aggregation of a carrier on which an anti-HMGB1 antibody is immobilized and thereby suppressing rise of a reagent blank caused by the aggregation, measurement reagent, etc.SOLUTION: A measuring method of HMGB1 in a specimen, etc. measures the concentration of HMGB1 in a specimen by bringing HMGB1 in the specimen into contact with an anti-HMGB1 antibody-immobilized carrier and measuring aggregation of the anti-HMGB1 antibody-immobilized carrier bound via HMGB1. The measuring method is characterized in that when HMGB1 in the specimen and the anti-HMGB1 antibody-immobilized carrier come into contact, 0.001% (w/v)-0.01% (w/v) of glycerin/propylene oxide/ethylene oxide adduct or 0.0054% (w/v)-0.022% (w/v) of glycerin/propylene oxide adduct coexists therein.SELECTED DRAWING: None (Grant)
Filing Date: Dec. 28, 2021
Publication Date: July 10, 2023
The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100
Disclaimer: Curated by HT Syndication.
