Japan, Feb. 24 -- REGENXBIO INC has got intellectual property rights for 'METHOD OF MEASURING INFECTIVITY OF REPLICATION-DEFICIENT VIRUS VECTOR AND VIRUS.' Other related details are as follows:
Application Number: JP,2024-139422
Category (FI): C12Q1/6806@Z,A61K35/76,C12Q1/6888@Z,C12Q1/686@Z,C12N15/864,100@Z,C12N15/867@Z,C12Q1/70,C12N15/861@Z,C12N15/11@Z,C12N15/863@Z,C12Q1/6851@Z,C12N15/10,100@Z,C12Q1/06
Stage: PROBLEM TO BE SOLVED: To provide an improved method for measuring infectivity of a replication-deficient virus and a virus vector.SOLUTION: A method for determining infectivity of a test composition including virus particles to infectivity of a reference composition including virus particles includes: a. a step of inoculating the test composition and a reference composition separately into a target cell; b. a step of cleaning the inoculated cell to remove virus particles outside the cell; c. a step of severally isolating a test nucleic acid sample and a reference nucleic acid sample from the target cell to which the test composition and reference composition have been inoculated; and d. a step of determining a ratio of virus genome copy (VGC):target cell genome copy (TCGC) in the test nucleic acid sample and the reference nucleic acid sample.SELECTED DRAWING: None (Grant)
Filing Date: Aug. 21, 2024
Publication Date: Nov. 19, 2024
The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100
Disclaimer: Curated by HT Syndication.
