Japan, Feb. 27 -- YOKOHAMA CITY UNIV has got intellectual property rights for 'PLASTICITY-INDUCING METHOD OF HEPATOCYTE.' Other related details are as follows:
Application Number: JP,2025-043070
Category (FI): C12N5/071,C12N5/10
Stage: PROBLEM TO BE SOLVED: To provide a method for manufacturing a hepatoblast, a hepatoblast, and a method for manufacturing a hepatocyte.SOLUTION: A method for manufacturing a hepatoblast includes a step of culturing an iPS cell-derived entodermal cell serum-free medium containing FGF2, HGF, oncostatin M and dexamethasone and differentiating the cell into a hepatoblast. As one aspect, the medium further contains nicotinamide, or the serum-free medium is serum-free differentiation medium, or an iPS cell is derived from a human, or a culture period of the iPS cell-derived entodermal cell is 5 days or more and less than 10 days.SELECTED DRAWING: Figure 2-1 (Grant)
Filing Date: March 18, 2025
Publication Date: June 24, 2025
The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100
Disclaimer: Curated by HT Syndication.
