Japan Intellectual Property Rights: PROCESS FOR THE SYNTHESIS OF QUINAZOLINE COMPOUNDS

Japan, Sept. 16 -- GENENTECH INC,F HOFFMANN-LA ROCHE AG has got intellectual property rights for 'PROCESS FOR THE SYNTHESIS OF QUINAZOLINE COMPOUNDS.' Other related details are as follows:

Application Number: JP,2025-158594

Category (FI): C07D403/04,A61K31/517,C07B61/00,300,A61P35/00,C07D401/14

Stage: PROBLEM TO BE SOLVED: To provide a method for synthesizing a compound useful for treating cancer.SOLUTION: Contacting a compound of formula (II) with an organomagnesium compound, transferring the obtained compound to a continuous stirred tank reactor (CSTR) containing a zinc compound, and contacting the thereby obtained compound with a compound of formula (III), a transition metal catalyst precursor and a chiral ligand to obtain the target compound.SELECTED DRAWING: None (Grant)

Filing Date: Sept. 24, 2025

Publication Date: Feb. 3

The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100

Disclaimer: Curated by HT Syndication.