Japan, March 5 -- RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL has got intellectual property rights for 'RECOMBINANT ADENO-ASSOCIATED VIRUS PRODUCT AND METHOD FOR TREATING LIMB-GIRDLE MUSCULAR DYSTROPHY 2.' Other related details are as follows:
Application Number: JP,2024-098061
Category (FI): C12N7/01,A61P21/00,A61K35/76,C12N15/864,100@Z,C12N1/21,C12N5/04,C07K14/47,C12N5/10,C12N1/19,A61P43/00,105,C12N15/12
Stage: PROBLEM TO BE SOLVED: To provide a product and a method for treating limb-girdle muscular dystrophy 2A.SOLUTION: In this method, a recombinant adeno-associated virus delivers DNA encoding protein having calpain 3 activity. A recombinant adeno-associated virus (rAAV) encoding the protein having calpain 3(CAPN3) activity is provided. The recombinant adeno-associated virus contains polynucleotide including a nucleotide sequence encoding the protein having CAPN3 activity. The nucleotide sequence encoding the protein having CAPN3 activity is at least 90% identical to a specific sequence or includes the specific sequence, for example.SELECTED DRAWING: None (Grant)
Filing Date: June 18, 2024
Publication Date: Sept. 10, 2024
The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100
Disclaimer: Curated by HT Syndication.
