Japan, Sept. 18 -- SANOFI SA has got intellectual property rights for 'STABLE, LOW-VISCOSITY ANTIBODY FORMULATIONS AND USES THEREOF.' Other related details are as follows:
Application Number: JP,2025-036010
Category (FI): A61K47/18,A61K47/02,A61K47/04,A61K39/395@N,A61K47/26,A61K47/20,A61K47/22,A61K47/34,A61K47/44,A61K9/08,A61K47/12,A61K39/395@M,A61K47/24
Stage: PROBLEM TO BE SOLVED: To provide an aqueous antibody formulation that exhibits improved stability and low viscosity, an injection device and a kit comprising the formulation, and a method for preparing the formulation.SOLUTION: An aqueous antibody formulation comprises: about 0.1 mg/mL to about 500 mg/mL of an antibody or an antigen-binding fragment thereof; about 1 mM to about 100 mM of a buffer selected from the group consisting of succinate, gluconate, histidine, citrate, and phosphate; and about 1 mM to about 750 mM of a salt selected from the group consisting of magnesium glutamate, magnesium acetate, magnesium aspartate, magnesium sulfate, sodium acetate, sodium aspartate, lithium acetate, lithium aspartate, lithium glutamate, and lithium sulfate. Therein the formulation has a pH of about 4 to about 8.SELECTED DRAWING: None (Grant)
Filing Date: March 7, 2025
Publication Date: June 10, 2025
The original document can be viewed at: https://www.j-platpat.inpit.go.jp/p0100
Disclaimer: Curated by HT Syndication.
